Monday, May 4, 2020

Thimerosal


Thimerosal is used a preservative in order to prevent the growth of dangerous microbes in case of contamination in mulit-dose vaccines. When each new needle is inserted to the vial. The thimerosal prevents contamination in in the vial when doses are drawn out. This is very important because if someone were to receive an injection that was contaminated it could potentially be very deadly (1).

Thimersosal has been used as a preservative in vaccines since 1940’ (J)s. However, since 1999 thimerosal has only remain in one type of vaccine. Which is the multi-dose Flu vaccine. The FDA decided to this in order to limit the amount of mercury (ethylmercury) children were exposed to, in other words it was a precautionary measure (1).

However, there were concerns in the media about the potential of mercury toxicity from multiple injections in the first few 6 months of life (J). However, people mistook the compound that thimerosal has called ethylmercury from methylmercury. While the two are related they have differences (3).

Methylmercruy is more toxic. It is able to pass the blood brain barrier and damage the nervous system since it is small in size (CHOP). It also has a longer half-life and more lipophilic so the body has a harder time excreting it from the body (3).

On the other hand, ethylmercury has a shorter half-life and the body is able to excrete much faster. It also does not accumulate in the body. Nor does it disease and because of it is bigger in size it is unable to cross the blood brain barrier so it is not able to damage the nervous system (2, 3).   

There were also many reputable studies conducted that have yet to show any link between mercury in vaccine causing autism in children. Different methods have methods have been used and some examined rates of autism in a state or country and compared the rates of autism before and after thimerosal was removed. The results showed that the number of children diagnosed with autism has not gone down since the removal of thiemrosal from vaccines (1). 

Resources:
  1. Centers for Disease Control and Prevention. (2013, February). Understanding Thimerosal, Mercury, and Vaccine Safety. Retrieved May 5, 2020, from https://www.cdc.gov/vaccines/hcp/patient-ed/conversations/downloads/vacsafe-thimerosal-color-office.pdf
  2. Children's Hospital of Philadelphia. (2014, November 5). Thimerosal. Retrieved May 6, 2020, from https://www.chop.edu/centers-programs/vaccine-education-center/vaccine-ingredients/thimerosal
  3. Clift, K., & Rizzolo, D. (2014). Vaccine myths and misconceptions. Journal of the American Academy of Physician Assistants, 27(8), 21-25. doi:10.1097/01.jaa.0000451873.94189.56